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Kuding Tea (Bitter Tea): What Research Shows About the Tea, Safety and Cautions

Kuding is a very bitter Chinese leaf tea. See what small trials and lab studies found, why its caffeine content is unclear, and the liver findings from high-dose extract in mice.

Content last updated . This page has not been medically reviewed.

Close-up of kuding tea (bitter tea): what research shows about the tea, safety and cautions

Safety first. Natural products can cause side effects and interact with medicines. Read herbal tea and extract safety before you use anything on this page.

Check before you drink: kuding tea research is mostly lab and animal work plus small trials, and whether it contains caffeine is not settled in the sources we read. One review of Ilex teas calls the large-leaved kuding a caffeinated tea-like drink and reports caffeine in it, while a popular claim that it is caffeine-free was not supported by a source we could read. [3] In mice, a high-dose kuding extract (not tea) raised liver weight and liver fat. [2] Kuding is not true tea from the tea plant. This page covers the TEA ITSELF and keeps it apart from extracts and supplements.

What kuding tea is

Kuding (Ku-Ding-Cha, "bitter tea") is a bitter-tasting Chinese herbal tea. [1][3] The name covers about 12 species in six plant families. [1] The two most common large-leaved kinds are Ilex latifolia Thunb. and Ilex kudingcha C.J. Tseng, both in the holly family (Aquifoliaceae); small-leaved kuding comes from Ligustrum species in a different family (Oleaceae). [1] The leaves are used. [1] The main compounds are triterpene saponins and polyphenols, and the makeup differs a lot between species, so one study may not apply to a different kuding. [1] This page covers the large-leaved Ilex kinds. There is no kuding herb page on this site.

Taste, caffeine and how to brew

QuestionWhat sources say
TasteBitter. Reviews call it a bitter-tasting tea. [1][3]
Caffeine per 8 fl oz (240 mL) cupNot found per cup. A 2018 review of Ilex drinks says methylxanthines, mainly caffeine and theobromine, are the main alkaloids in large-leaved kuding, with low overall alkaloid content, and quotes a total of about 7% to 9% with caffeine 3% to 6% (the unit and basis are not clear to us). [3] Other pages say kuding is caffeine-free, but we did not find a measurement that settles it. Treat the caffeine level as unknown.
Water temperature and steeping timeProper evidence not found in the sources we read.
Amount of leaf per cupProper evidence not found. The trials in the review below used from under 1 g to 150 g of kuding a day in different forms, so they are not a guide to a cup. [4]
Cold brew / icedProper evidence not found.
Hot-drink noteNo source ties kuding to the very hot drink finding. IARC's finding concerns any drink above about 149 °F (65 °C); see hot tea and esophageal cancer risk.

What research found about the tea itself

QuestionWhat the source foundStrength of evidenceForm and who was studied
Blood fats (cholesterol, triglycerides)A 2022 meta-analysis of 8 randomized trials with 716 people found lower total cholesterol, triglycerides and LDL cholesterol with kuding than with the comparison, and no clear change in HDL. [4]Promising but limitedTrials in China, 2 to 8 weeks, compared with drugs such as statins, forms and doses varied
Weight and blood sugarReviews describe these effects mainly in mice and cell studies. [1][5]Lab or animal onlyMice, cells
Antioxidant, anti-inflammatory and anticancer activityReported in lab and animal studies; the review says the human relevance is unclear. [1]Lab or animal onlyMice, cells
Liver safety of high-dose extractIn mice fed a high-fat diet, a kuding extract (encapsulated in cyclodextrin) increased liver weight and fat and raised levels of liver enzymes that process drugs; in liver cells it was toxic in a dose-dependent way. [2]Extract only (animal and cell)Mice and liver cells; not tea
Long drinking historyA review says traditional kuding tea as a beverage has a long history of consumption and is generally considered safe. [1]Insufficient evidenceTradition, not a safety study

Limits: the meta-analysis authors say the trials were of poor quality, with unclear random assignment and blinding, all in China, and the comparison was often a drug rather than a placebo. [4] A trial against a drug does not show kuding works on its own. The review authors also say most of the other health claims come from lab and animal studies. [1]

Check before you drink

  • Caffeine. Unknown for kuding in the sources we read (see above). If you must limit caffeine, treat it with the same care as caffeinated tea. The NHS says pregnant people should have no more than 200 mg of caffeine a day. [6] The FDA says people vary widely in caffeine sensitivity. [7]
  • Pregnancy, breastfeeding, babies and children. No kuding-specific source was found. Ask a clinician; see herbal tea in pregnancy and herbal tea for babies and children.
  • Medicines and liver. The mouse study found the extract raised levels of liver enzymes that process many drugs, which the authors say may interfere with how drugs are handled. This was a very high extract dose in mice, not a cup of tea. [1][2] If you take regular medicines or have liver disease, ask a pharmacist. See liver and kidney cautions.
  • Identity. Different plants are sold as kuding, from different families. Check the label for the Latin name. [1]
  • Kidney, iron, allergy, surgery, metals and pesticides. Not described in the sources we read. Not described is not proof of none.

Tea, capsule or extract?

The animal liver findings are for a concentrated extract, and the lipid trials used mixed forms. A cup of kuding is not the same as an extract. See tea vs tincture vs capsule.

Buying and storing

  • Look for the Latin name (Ilex latifolia or Ilex kudingcha) and the part (leaf). See reading an herbal tea label.
  • Drying and storage change the leaf chemistry in lab studies of kuding. [1]
  • For storage see storing herbal tea.

Related pages

TeaIlex kudingcha, Ilex latifolia

What research found and what to check: Kuding Tea (Bitter Tea)

Findings about drinking the tea itself, kept apart from capsules, extracts and concentrated supplements. Each card says what was studied, in whom, and how strong the evidence is.

Kuding tea and blood fats (cholesterol, triglycerides)

Preliminary or mixed

A 2022 meta-analysis of 8 randomized trials (716 people) found lower total cholesterol, triglycerides and LDL with kuding than with the comparison, and no clear HDL change.

Supplements: A trial against a drug does not show kuding works alone; do not replace cholesterol medicines.

Weight and blood sugar (animal and lab)

Lab or animal research only

Reviews describe lower body weight, blood sugar and fat gain in mice, and effects on gut bacteria, largely from extracts.

Supplements: No human trial of the tea for weight or blood sugar was found.

Antioxidant, anti-inflammatory and anticancer activity (lab)

Lab or animal research only

Lab and animal studies report these activities from kuding polyphenols and saponins.

Is it caffeine-free? Unclear

Not enough evidence

One 2018 review lists large-leaved kuding among caffeinated Ilex drinks, with caffeine among its main alkaloids at low overall alkaloid content; the figures given are unclear. No per-cup measurement was found.

Traditional bitter tea with a long drinking history

Not enough evidence

A review says traditional kuding tea as a beverage has a long history of consumption and is generally considered safe.

Connected topics

Open a group to see how each topic connects and how strong the evidence is.

Health goals (1)
  • Cholesterol BalancePreliminary or mixed

    A meta-analysis of 8 small Chinese trials found lower total cholesterol, triglycerides and LDL; trial quality was poor and the comparison was often a drug.

Body systems (2)
  • Cardiovascular SystemPreliminary or mixed

    Lipid markers improved in a meta-analysis of small trials.

  • Heart & CirculationPreliminary or mixed

    Blood fat markers improved in small trials; effect on heart disease not studied.

Functional actions (3)
  • Anti-InflammatoryLab or animal research only

    Anti-inflammatory activity reported in lab and animal work only.

  • AntioxidantLab or animal research only

    Antioxidant activity reported in lab and animal work only.

  • Cardiovascular SupportPreliminary or mixed

    Blood fat markers improved in small trials of kuding.

Biomarkers (2)
  • LDL CholesterolPreliminary or mixed

    LDL was lower in a meta-analysis of 8 small trials; quality poor.

  • TriglyceridesPreliminary or mixed

    Triglycerides were lower in the meta-analysis; very varied results between trials.

Conditions & symptoms (1)
  • HyperlipidemiaPreliminary or mixed

    Eight small Chinese trials in people with high blood fats and related conditions found lower cholesterol and triglycerides; trial quality was poor and forms and doses varied.

Documented risks and interactions (3)
  • High-dose extract and the liver (mice). In mice on a Western-type diet, a kuding extract encapsulated in cyclodextrin raised liver weight and liver fat and increased levels of liver enzymes that process drugs (CYP3A, GSTA1); in liver cells it was toxic in a dose-dependent way.
  • Species mix-ups and variable chemistry. About 12 species from six families are sold as kuding; large-leaved Ilex kinds and small-leaved Ligustrum kinds differ, and chemistry varies with species, origin, drying and storage.
  • Caffeine in pregnancy (if caffeine is present). NHS advises no more than 200 mg of caffeine a day in pregnancy; the FDA says people vary widely in sensitivity.

Explore all 94 teas

Frequently asked questions

Is kuding tea caffeine-free?

We could not confirm it. One 2018 review of Ilex drinks lists kuding among caffeinated drinks and reports caffeine in it, but the figures are unclear. [3] We found no measurement per cup.

Does kuding tea lower cholesterol?

A 2022 meta-analysis of 8 small randomized trials in China found lower total cholesterol, triglycerides and LDL, but the trials were of poor quality and used different forms and doses. [4] Do not stop or swap cholesterol medicines on your own.

Is kuding tea safe for the liver?

Traditional tea drinking is described as long-used and generally considered safe. [1] A high-dose extract raised liver weight and fat in mice, which is not the same as tea. [2] Ask a clinician if you have liver disease.

Is kuding tea safe in pregnancy or with medicines?

We found no kuding-specific source on pregnancy. The mouse study suggests the extract can affect drug-processing enzymes. [1][2] Ask a pharmacist or clinician.

Does kuding tea help with weight loss?

Proper evidence not found in human trials of the tea. Weight effects are described mainly in mice and cell studies. [1][5]

References
  1. Wüpper S, Lüersen K, Rimbach G. Chemical composition, bioactivity and safety aspects of kuding tea: from beverage to herbal extract. Nutrients. 2020. Full text read via Europe PMC. Read 2026-10-23.
  2. Wüpper S, et al. High dietary kuding tea extract supplementation induces hepatic xenobiotic-metabolizing enzymes: a 6-week feeding study in mice. Nutrients. 2019. Abstract read. Read 2026-10-23.
  3. Gan RY, et al. Health benefits of bioactive compounds from the genus Ilex, a source of traditional caffeinated beverages. Nutrients. 2018. Full text read via Europe PMC. Read 2026-10-23.
  4. Jiang Z, Lu Z, Wang T, et al. Lipid-lowering efficacy of kuding tea in patients with metabolic disorders: a systematic review and meta-analysis of randomized controlled trials. Front Nutr. 2022. Full text read via Europe PMC. Read 2026-10-23.
  5. Liu X, Lin X, Fei T, et al. Chemical components, health-promoting effects and industrial application of a Chinese bitter tea (kuding tea): a comprehensive review. Food Chem. 2025. Abstract read only. Read 2026-10-23.
  6. NHS. Foods to avoid in pregnancy. Caffeine section. Read 2026-10-23.
  7. US Food and Drug Administration. Spilling the beans: how much caffeine is too much?. Read 2026-10-23.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.