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Kampo and TCM: Shared Roots and Differences

How Japanese Kampo medicine and Chinese medicine share roots but differ in who prescribes, how products are regulated and how they are tested, with safety notes.

Content last updated . This page has not been medically reviewed.

Quick answer
Kampo is the traditional herbal medicine of Japan. A Japanese regulation paper describes Kampo as based on Chinese medicine and as having evolved into a Japanese original style over a long period. [1] So the two are related, but they are not the same thing in daily practice. This page compares them. It is information only. For the Japanese tradition on its own, see Kampo Medicine.

Who prescribes it

This is the biggest practical difference.
  • In Japan. Traditional physicians were abolished in Japan, so most Kampo treatment now comes from physicians who learned modern Western medicine. They prescribe Kampo extract products based on a Western medical diagnosis. The authors say this differs from other East Asian countries. [2]
  • Insurance. Prescription Kampo formulations are prescribed in general practice under the National Health Insurance reimbursement system. [1]
  • In China and elsewhere. Practitioners of Chinese medicine in many places make their own assessment in the tradition's terms, using patterns and tongue and pulse. See Traditional Pattern Differentiation in TCM and TCM Consultation. We did not find a source we could read that compares the two diagnostic styles in detail, so we stay with the prescriber difference above.

Testing: how the evidence looks

A 2022 review explains that Kampo products were approved without scientific clinical evidence because of long experience with them as decoctions. In the 1990s they were re-evaluated nationally, and from 2000 onward many randomized trials appeared. [2] Trials do exist, and they do not always favor the formula. In one double-blind, placebo-controlled trial of 171 people with moderate acute diverticulitis, the Kampo formula daiobotanpito added to antibiotics did not improve the primary treatment success rate compared with placebo (P = .348). [3] It showed some secondary differences in inflammation markers and the time to eat in people with abscesses, which is a hint, not proof. [3]

The evidence label depends on the formula and the condition. There is no single verdict on Kampo. Chinese formulas have their own mixed trial record; see Chinese Herbal Medicine.

The difference at a glance

QuestionKampo (Japan)Chinese medicine
Typical prescriberPhysician trained in Western medicine, Western diagnosis [2]Varies by country; see the qualifications page
Legal statusPharmaceuticals, insurance-covered [1]Differs by country
EvidenceMany trials since 2000, results mixed [2][3]Large literature of uneven quality [5]

For Korea, see Korean Traditional Medicine (Hanbang).

Frequently asked questions

Is Kampo the same as Chinese medicine?

No. It is based on Chinese medicine but developed into a Japanese form. [1] Its modern prescribers are mostly Western-trained doctors. [2]

Is Kampo regulated?

In Japan, yes: Kampo medicines are classified as pharmaceuticals. [1]

Does Kampo work?

It depends on the formula and the condition. A double-blind trial of one formula in diverticulitis found no added benefit on its main measure. [3]

Can Kampo cause side effects?

Yes. Liver dysfunction and interstitial pneumonia have been reported. [4]

Can I use Kampo with my medicines?

Ask a pharmacist or doctor first, since interactions can occur. [4]

More details: evidence, limits and cautions

The details behind this page: cautions, limits of the evidence and where sources disagree. Open any note to read it.

Regulation: Kampo medicines are pharmaceuticals
In Japan, Kampo medicines are classified as pharmaceuticals. Over-the-counter Kampo products can be bought for self-care. [1] The Ministry of Health, Labour and Welfare publishes approval standards for over-the-counter Kampo products, which list 294 formulas, and crude drugs and Kampo extracts are listed in the Japanese Pharmacopoeia. [1] For how herbal products are handled elsewhere, see How Supplements Are Regulated.
Safety: natural does not mean harmless
  • Japanese pharmacists' training material says Kampo adverse effects are rare compared with Western medicine, but serious events such as liver dysfunction and interstitial pneumonia have been reported in increasing trends. [4]
  • Some effects trace to single ingredients: glycyrrhizin in licorice can cause pseudoaldosteronism, and geniposide in Gardenia fruit has been linked to mesenteric phlebosclerosis. [4]
  • The same paper warns that Kampo was not developed to be used with Western medicine, so drug interactions can happen. [4]

Do not combine herbal products with prescribed medicines without asking a pharmacist or doctor, and do not stop any prescription on your own. For product quality see Chinese Herbal Products: Quality, Contamination and Medicine Interactions and Liver Safety & Supplements.

References
  1. Regulation of traditional herbal medicinal products in Japan, J Ethnopharmacol 2016. PubMed 25043783. Read 2026-10-22.
  2. Clinical studies of traditional Japanese herbal medicines (Kampo): Need for evidence by the modern scientific methodology, Integr Med Res 2022. PubMed 34136346. Read 2026-10-22.
  3. Daiobotanpito combined with antibiotic therapy for acute diverticulitis: randomized, double-blind, placebo-controlled trial, Sci Rep 2025. PubMed 40595170. Read 2026-10-22.
  4. Education Program of Kampo-medicine for Undergraduates in Preparation for Clinical Setting, Yakugaku Zasshi 2017. PubMed 26935080. Read 2026-10-22.
  5. An evidence map on traditional medicine across health outcomes, Integr Med Res 2024. PubMed 39219985. Read 2026-10-22.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.