Holistic Remedies · Ingredient
Perillyl alcohol
Formula: C10H16O · MW: 152.237 · Drug-likeness: 0.602
⚗️ Identity
Name
Perillyl alcohol
Aliases / Synonyms
536-59-4; Perilla alcohol; Perillol; Isocarveol; p-Mentha-1,8-dien-7-ol; Hydrocumin alcohol; 1-Cyclohexene-1-methanol, 4-(1-methylethenyl)-; Dihydrocuminyl alcohol; Iso-carveol
🧪 Chemistry
Molecular Weight
152.2370
LogP
2.2813
Drug-likeness
0.602
Oral Bioavailability
46.2390
H-Bond Acceptors
1
H-Bond Donors
1
Rotatable Bonds
2
🔗 External References
5
Clinical Trials
2
Meta-Analyses
4
PubMed References
Top Conditions Studied with Perillyl alcohol
📋 Sample Trials
NCT00608634
Topical Perillyl Alcohol in Treating Patients With Sun Damaged Skin and Actinic Keratoses
Completed · Phase 2 · Precancerous Condition
NCT00002862
Perillyl Alcohol in Treating Patients With Refractory Cancer
Completed · Phase 1 · Lymphoma|Unspecified Adult Solid Tumor,
NCT00003219
Perillyl Alcohol in Treating Patients With Metastatic Breast Cancer
Completed · Phase 2 · Breast Cancer
NCT00003238
Perillyl Alcohol in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
Completed · Phase 2 · Prostate Cancer
NCT00003769
Perillyl Alcohol Followed by Surgery in Treating Patients With Stage II or Stage III Pancreatic Cancer
Completed · Phase 2 · Pancreatic Cancer
📊 Sample Meta-Analyses
CRD42018082207
Limonene, perillyl alcohol, perillic acid and perillaldehyde as anticancer agents: a systematic review
Cancer treatment Cancer prevention
CRD42021255527
Perillyl alcohol for cancer treatment
Cancer treatment
📚 Sample References
PMID 33649109
Perillyl alcohol reduces parasite sequestration and cerebrovascular dysfunction during experimental cerebral malaria
Antimicrob Agents Chemother · 2021
PMID 34929480
Perillyl alcohol inhibits keratinocyte proliferation and attenuates imiquimod-induced psoriasis like skin-inflammation by modulating NF-κB and STAT3 signaling pathways
Int Immunopharmacol · 2021
PMID 35030388
Perillyl alcohol attenuates rheumatoid arthritis via regulating TLR4/NF-κB and Keap1/Nrf2 signaling pathways: A comprehensive study onin-vitro and in-vivo experimental models
Phytomedicine · 2022
PMID 36070663
Perillyl alcohol attenuates chronic restraint stress aggravated dextran sulfate sodium-induced ulcerative colitis by modulating TLR4/NF-κB and JAK2/STAT3 signaling pathways
Phytomedicine · 2022
🏥 Linked Health Topics 3 · matched via study conditions