Holistic Remedies · Ingredient
Oxytocin
Formula: C43H66N12O12S2 · MW: 1007.206999999999 · Drug-likeness: 0.067
⚗️ Identity
Name
Oxytocin
Aliases / Synonyms
50-56-6; Pitocin; Endopituitrina; Ocytocin; Syntocinon; Oxytocinum; Orasthin; Oxystin; alpha-Hypophamine
🧪 Chemistry
Molecular Weight
1007.2070
LogP
-3.6086
Drug-likeness
0.067
H-Bond Acceptors
15
H-Bond Donors
12
Rotatable Bonds
17
🔗 External References
332
Clinical Trials
98
Meta-Analyses
5
PubMed References
Top Conditions Studied with Oxytocin
📋 Sample Trials
NCT03578263
Carbetocin Versus Oxytocin and Ergometrine for the Prevention of Postpartum Hemorrhage
Completed · Cesarean Section Complications
NCT01012167
Oxytocin or Galantamine Versus Placebo for the Treatment of Negative Symptoms and Cognitive Impairments in Schizophrenia
Completed · Phase 2 · Schizophrenia
NCT00263796
An fMRI Study of the Effect of Intravenous Oxytocin vs. Placebo on Response Inhibition and Face Processing in Autism
Completed · Phase 1 · Autism
NCT00468520
Adjuvant Oxytocin for Preinduction Ripening With a Foley catheter--a Clinical Trial
Completed · Pregnancy|Induced Labor|Cervical Ripenin
NCT00481533
Ergot and Oxytocin During Cesarean Delivery Following Failure to Progress in Labour
Completed · Blood Loss, Surgical
NCT00490802
Intranasal Oxytocin in the Treatment of Autism
Completed · Phase 2 · Autism
📊 Sample Meta-Analyses
CRD42014013196
Misoprostol versus ergometrine-oxytocin for preventing postpartum hemorrhage: systematic review and meta-analysis of randomized controlled trials and the implications for developing countries
Postpartum hemorrhage (PPH) is a major cause of maternal mortality, accounting f
CRD42015016979
Intranasal oxytocin for autism spectrum disorders (ASD) [Cochrane Protocol]
The Cochrane Developmental, Psychosocial and Learning Problems Group
CRD42015024068
Oxytocin for preventing postpartum haemorrhage (PPH) in non-facility birth settings [Cochrane Protocol]
The Cochrane Pregnancy and Childbirth Group
CRD42015026567
Continuous versus pulsatile oxytocin administration for the augmentation of labour [Cochrane Protocol]
The Cochrane Pregnancy and Childbirth Group
CRD42015027864
The relationship between central and peripheral oxytocin concentrations
Oxytocin concentrations, Psychiatric conditions (e.g., autism spectrum disorders
CRD42015029461
Oxytocin bolus versus continuous infusion for the prophylactic reduction of blood loss and uterine atony during caesarean delivery
Excessive blood loss and uterine atony are common complications in women undergo
📚 Sample References
PMID 30262887
Neurochemical evidence for differential effects of acute and repeated oxytocin administration
Mol Psychiatry · 2021
PMID 34483895
Oxytocin Attenuates Methamphetamine-Induced Apoptosis via Oxytocin Receptor in Rat Hippocampal Neurons
Front Pharmacol · 2021
PMID 34733156
Protective Effect of Oxytocin on Ventilator-Induced Lung Injury Through NLRP3-Mediated Pathways
Front Pharmacol · 2021
PMID 34863977
Oxytocin suppresses epithelial cell-derived cytokines production and alleviates intestinal inflammation in food allergy
Biochem Pharmacol · 2022
PMID 34925023
Oxytocin Protects Against Isoproterenol-Induced Cardiac Hypertrophy by Inhibiting PI3K/AKT Pathway via a lncRNA GAS5/miR-375-3p/KLF4-Dependent Mechanism
Front Pharmacol · 2021
🏥 Linked Health Topics 12 · matched via study conditions
Aging
phenotype
Alcohol Use Disorder
disease
Anorexia Nervosa
disease
Antisocial Personality Disorder
disease
Cardiac Arrhythmia
phenotype
Autistic Disorder
disease
Depressive Disorder
disease
Fragile X Syndrome
syndrome
Irritable Mood
phenotype
Obesity
syndrome
Pain
phenotype
Postpartum Hemorrhage
phenotype