Mayonnaise: Nutrients, What Research Shows and Safety
Mayonnaise as a food: USDA calories and fat profile, vitamin K and warfarin, egg allergy, raw-egg Salmonella risk in homemade versions, and what research shows.
Content last updated . This page has not been medically reviewed.

Mayonnaise is a thick sauce made by whisking oil into egg yolk with an acid such as vinegar or lemon juice. It is an emulsion, which means oil and a water-based liquid held together as a smooth cream. Reviews of its safety describe it as a raw-egg product when made at home. [6] USDA describes regular mayonnaise as a salad dressing. [1] Because it is mostly oil, it is a high-calorie condiment rather than a health food, and the main safety questions are egg allergy and, for homemade versions, raw egg. This page separates the store-bought product from home recipes and from hype.
Read this first
- It is mostly fat. USDA lists about 75 g of fat per 100 g and about 94 kcal in 1 tablespoon (13.8 g). [1]
- Homemade mayonnaise made with raw eggs can carry Salmonella. The FDA says fresh eggs, even with clean shells, may contain Salmonella, and recommends pasteurized eggs or egg products for recipes that use raw or undercooked eggs. [2] Children, older adults, pregnant women and people with weakened immune systems face greater risk. [2] The NHS says homemade mayonnaise made with raw egg is acceptable in pregnancy only if British Lion or Laid in Britain eggs are used. [3]
- Commercial mayonnaise is acidic, and a review of the literature found it very safe. The absence of reports of illness linked directly to commercially prepared acidic dressings supports that, according to a review in the Journal of Food Protection. [5]
- Egg allergy: egg is a major food allergen. [11] For trouble breathing or swelling of the face or throat, call 911 (or your local emergency number).
- Warfarin: USDA lists 163 micrograms of vitamin K per 100 g, about 22 micrograms in a tablespoon. [1] People on warfarin are advised to keep vitamin K intake steady. [8]
What is in it (USDA values)
The values below are for regular mayonnaise (USDA FoodData Central item 171009, SR Legacy, listed as "salad dressing, mayonnaise, regular"). [1] The serving column is the USDA household portion of 1 tablespoon, 13.8 g. USDA also lists 1 packet (10 g) and 1 cup (220 g).
| Nutrient | Per 100 g | Per 1 tbsp (13.8 g) | % Daily Value per serving |
|---|---|---|---|
| Energy | 680 kcal | 94 kcal | not set |
| Total fat | 74.9 g | 10.3 g | 13% |
| Saturated fat | 11.7 g | 1.6 g | 8% |
| Monounsaturated fat | 16.8 g | 2.3 g | no DV |
| Polyunsaturated fat | 44.7 g | 6.2 g | no DV |
| Omega-3 (ALA) | 5.3 g | 0.74 g | no DV |
| Cholesterol | 42 mg | 5.8 mg | 2% |
| Sodium | 635 mg | 88 mg | 4% |
| Vitamin K | 163 mcg | 22 mcg | 19% |
| Vitamin E (alpha-tocopherol) | 3.28 mg | 0.45 mg | 3% |
| Choline | 34.2 mg | 4.7 mg | 1% |
| Protein | 0.96 g | 0.13 g | 0% |
% Daily Value uses the FDA 2016 Daily Values; the serving figures are the 100 g values multiplied by 0.138. USDA lists 0.19 g of trans fat per 100 g. [1] The USDA item also shows a vitamin D value that we could not confirm as plausible for mayonnaise, so we do not repeat it. Brands, "light" versions and homemade recipes differ from this average.
Plant compounds: we did not read a source that measured named plant compounds in mayonnaise, so none are listed.
What research says
| Health goal | What the sources found | Strength of evidence | What was studied |
|---|---|---|---|
| Heart health and LDL cholesterol | Proper evidence not found in the sources we read for mayonnaise itself. The American Heart Association says replacing saturated fat with unsaturated fat lowers cardiovascular disease. [15] USDA lists mostly unsaturated fat in this mayonnaise, [1] but the oil type depends on the brand. | Insufficient evidence for mayonnaise | Not applicable |
| Eggs, dietary cholesterol and death | A 2022 meta-analysis plus a cohort of 27,078 men linked each extra 300 mg of dietary cholesterol a day to a 10% higher risk of death (hazard ratio 1.10) and each extra 50 g egg a day to a 6% higher risk (1.06). [10] These are observational and cannot prove cause. Mayonnaise gives about 6 mg of cholesterol a tablespoon. [1] | Mixed (observational) | Whole eggs and dietary cholesterol, not mayonnaise |
| Food safety of commercial mayonnaise | A review found Salmonella, E. coli O157:H7 and Listeria die when added to mayonnaise and dressings, mainly because of acetic acid and low pH. [5] | Established for commercial acidic products in the lab | Lab inoculation studies and a literature review |
| Food safety of raw-egg homemade mayonnaise | A review says outbreaks are mostly linked to eggs and raw-egg products such as mayonnaise, and that there is no agreed critical pH limit for controlling Salmonella. [6] | Documented risk | Review of lab and outbreak literature |
| Weight loss, skin, "seed oil" claims | Proper evidence not found in the sources we read. | No good evidence of benefit found | Not applicable |
Eaten as food vs other forms. Mayonnaise is eaten in small amounts as a condiment. The studies above are about eggs, cholesterol or bacteria, not about mayonnaise as a heart or health food.
How much is a normal serving
USDA's household portion is 1 tablespoon (13.8 g), about 94 kcal, and a single-serve packet is 10 g. [1] That is information from USDA, not a prescription. For fat limits, WHO says saturated fat should be under 10% of energy for people aged 2 and older, [13] and the NHS gives 30 g a day (men) and 20 g a day (women) as the saturated fat maximum. [14] One tablespoon of this mayonnaise has 1.6 g of saturated fat. [1]
Safety, allergy and medicines
- Raw egg and Salmonella: CDC lists children under 5, adults 65 and older, adults 50 and older with conditions like heart disease, and people with weakened immune systems as higher-risk groups for Salmonella. [4] The FDA says Salmonella usually causes diarrhea, fever, cramps and vomiting 12 to 72 hours after infection, and can be severe. [2]
- Egg allergy: egg must be named on packaged food labels in the US. [11] The NHS lists eggs among the most common food allergens and says to call 999 (911 in the US) for swelling of the lips, mouth or throat or struggling to breathe. [12] Mayonnaise is an egg-based sauce, so people with egg allergy should avoid it unless a product is labeled egg-free (vegan "mayo" is a different product).
- Soy: many mayonnaises are made with soybean oil; the FDA's allergen page says highly refined oils are not covered by the labeling rule. [11] We did not read a source on soy-oil mayonnaise and soy allergy, so ask an allergist.
- Warfarin and vitamin K: a review says plant oils and prepared foods made with them, such as salad dressings, add vitamin K, and that a constant intake is the accepted practice on warfarin. [8] A 53-patient study found each 100 mcg a day rise in dietary vitamin K was linked to a lower INR (blood clotting test) by 0.2, and that a consistent intake reduces variability. [9] Talk to your anticoagulation clinic; this is information, not advice.
- Pregnancy: use pasteurized-egg or Lion-mark products; the NHS advice is above. [3]
- Children: the saturated fat limit applies from age 2. [13]
- Kidney disease and diabetes: USDA lists 0.57 g of carbohydrate and 20 mg of potassium per 100 g. [1] We did not read advice specific to mayonnaise; ask your clinician.
- Sodium: about 88 mg per tablespoon (4% of the Daily Value). [1]
Choosing, storing and food safety
- Use pasteurized eggs for homemade mayonnaise if you serve it to anyone at higher risk. [2] A review found acidity helps but pH alone is not a reliable guard for raw-egg versions. [6]
- Lab results on storage are not a kitchen rule. In one lab study, E. coli O157:H7 added to commercial mayonnaise became undetectable after 72 hours at 25 C but stayed detectable for up to 35 days at 7 C. [7] We did not read an official storage time for opened jars, so follow the label.
- The FDA advises keeping eggs refrigerated at 40 F or below and not leaving egg dishes out for more than 2 hours (1 hour above 90 F). [2]
Related pages
Health connections for Mayonnaise
What research links to eating or drinking this food, and how strong the evidence is. Many studies are observational or use juice, powder, oil or extracts rather than the food as eaten; each card says which.
Commercial mayonnaise food safety
Lab or animal research onlyA literature review found the main food poisoning bacteria die in acidic commercial mayonnaise and dressings, mostly because of acetic acid and low pH.
Supplements: Based on lab inoculation studies and a review, not human trials.
Eggs, dietary cholesterol and mortality
Preliminary or mixedA 2022 meta-analysis and cohort linked higher dietary cholesterol and egg intake to higher mortality; observational only.
Supplements: The studies are about whole eggs, not mayonnaise.
Mayonnaise and heart health
Not enough evidenceProper evidence not found in the sources we read for mayonnaise itself.
Supplements: The American Heart Association supports replacing saturated fat with unsaturated fat in general.
Connected topics
Open a group to see how each topic connects and how strong the evidence is.
Body systems (1)
- Digestive SystemDocumented risk
Raw-egg mayonnaise can carry Salmonella, which causes diarrhea, fever and cramps.
Body parts (1)
- GutDocumented risk
Salmonella infection from raw egg products affects the gut.
Root causes (1)
- Medication Side EffectsDocumented risk
Vitamin K in mayonnaise matters for people on warfarin, who are advised to keep intake steady.
Conditions & symptoms (2)
- Food AllergyDocumented risk
Egg is a major food allergen and mayonnaise is egg-based.
- Salmonella InfectionsDocumented risk
Raw-egg homemade mayonnaise can carry Salmonella.
Documented risks and interactions (4)
- Raw-egg homemade mayonnaise and Salmonella. A review says outbreaks are mostly linked to eggs and raw egg products such as mayonnaise; the FDA recommends pasteurized eggs for raw-egg recipes.
- Egg allergy and mayonnaise. Egg is a major food allergen that must be named on US labels; mayonnaise is an egg-based sauce.
- Vitamin K in mayonnaise and warfarin. USDA lists 163 mcg of vitamin K per 100 g (about 22 mcg a tablespoon). Steady vitamin K intake is the usual goal on warfarin.
- Mayonnaise in pregnancy. The NHS says homemade mayonnaise with raw egg is acceptable only with British Lion or Laid in Britain eggs.
Frequently asked questions
Is store-bought mayonnaise safe?
A review of the literature found no reports of illness linked directly to commercially prepared acidic dressings and sauces, and found that the main bacteria die in them. [5] Follow the label for storage.
Is homemade mayonnaise with raw egg safe?
It carries a Salmonella risk. The FDA recommends pasteurized eggs for recipes that use raw eggs. [2] The NHS says raw-egg homemade mayonnaise is acceptable in pregnancy only with British Lion or Laid in Britain eggs. [3]
Does mayonnaise have vitamin K, and does it matter on warfarin?
USDA lists about 22 mcg per tablespoon, 19% of the Daily Value. [1] On warfarin, steady vitamin K intake is the usual goal. [8] Ask your anticoagulation clinic.
Can I eat mayonnaise with an egg allergy?
Usually not. Mayonnaise is made from egg yolk, and egg is a major allergen that must be named on US labels. [11] [6] Call 911 for trouble breathing or swelling of the face or throat.
Is mayonnaise bad for cholesterol?
We found no trial of mayonnaise and cholesterol. USDA lists 42 mg of cholesterol per 100 g (about 6 mg a tablespoon). [1] The larger factors are the total fat and calories you eat.
References
- U.S. Department of Agriculture. FoodData Central: Salad dressing, mayonnaise, regular (SR Legacy, FDC 171009). April 2018 release. Values taken from the USDA data file prepared for this site, 2026-10-24.
- FDA. What you need to know about egg safety. Content current as of 5 March 2024. Read 2026-10-24.
- NHS. Foods to avoid in pregnancy. Last reviewed 15 June 2026. Read 2026-10-24.
- CDC. About Salmonella infection. 4 October 2024. Read 2026-10-24.
- Smittle RB. Microbiological safety of mayonnaise, salad dressings, and sauces produced in the United States: a review. J Food Prot 2000 (abstract read via Europe PMC). Read 2026-10-24.
- Keerthirathne TP et al. A review of temperature, pH, and other factors that influence the survival of Salmonella in mayonnaise and other raw egg products. Pathogens 2016 (abstract read via Europe PMC). Read 2026-10-24.
- Weagant SD, Bryant JL, Bark DH. Survival of Escherichia coli O157:H7 in mayonnaise and mayonnaise-based sauces at room and refrigerated temperatures. J Food Prot 1994 (abstract read via Europe PMC). Read 2026-10-24.
- Booth SL, Centurelli MA. Vitamin K: a practical guide to the dietary management of patients on warfarin. Nutr Rev 1999 (abstract read via Europe PMC). Read 2026-10-24.
- Khan T et al. Dietary vitamin K influences intra-individual variability in anticoagulant response to warfarin. Br J Haematol 2004 (abstract read via Europe PMC). Read 2026-10-24.
- Zhao B et al. Associations of dietary cholesterol, serum cholesterol, and egg consumption with overall and cause-specific mortality: systematic review and updated meta-analysis. Circulation 2022 (abstract read via Europe PMC). Read 2026-10-24.
- FDA. Food allergies. Content current as of 11 March 2026. Read 2026-10-24.
- NHS. Food allergy. Last reviewed 20 August 2026. Read 2026-10-24.
- World Health Organization. WHO updates guidelines on fats and carbohydrates. 17 July 2023. Read 2026-10-24.
- NHS. Eat less saturated fat. Last reviewed 19 June 2023. Read 2026-10-24.
- Sacks FM et al., American Heart Association. Dietary fats and cardiovascular disease: a presidential advisory. Circulation 2017 (abstract read via Europe PMC). Read 2026-10-24.