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Rasa Shastra and Bhasma: Herbo-Mineral Preparations and Their Risks

What rasa shastra and bhasma are in Ayurveda, why herbo-mineral products with mercury, lead or arsenic are a documented safety issue, and what regulators and studies say.

Content last updated . This page has not been medically reviewed.

Urgent first

If someone has taken a mineral or metal-containing remedy and is very unwell, or a baby or young child has been given one, seek emergency care. In the US call 911, or call Poison Help at 1-800-222-1222. FDA also advises talking with a health care provider or a poison center if you have used Ayurvedic products and have possible symptoms of heavy metal poisoning. [1] Bring the product and its packaging. See poisoning: what to do first.

What rasa shastra and bhasma are

Rasa shastra (also written rasashastra) is the section of Ayurvedic medicine that deals with formulations containing minerals and metals, particularly parad, which is mercury. [2] A review notes that, according to the Ayurvedic Formulary of India, the most widely used heavy metals are mercury, arsenic and lead. [3]

Bhasma is one of these preparations. It is an ash obtained through incineration, made from a starting material that goes through purification and then a reaction phase involving herbal extracts or other minerals. [4] A 2014 review dates bhasma in the Indian subcontinent to the 7th century CE and says it is widely recommended for chronic ailments. [5]

The tradition's position is that metals are used only after purification. [6] This page describes the topic for safety information. It gives no preparation steps, and these products are not something to make or use at home.

Evidence labels used here: traditional use only, preclinical, evidence of harm, insufficient evidence.

Why this is a safety issue

  • Not labeled. FDA states that Ayurvedic products typically are not labeled to contain heavy metals such as lead, mercury or arsenic. [7]
  • Higher rates in rasa shastra products. In the 2008 study of 193 Ayurvedic medicines bought online, 40.6% of rasa shastra products had detectable metals versus 17.1% of others, and the median mercury concentration was much higher (20,800 versus 34.5 micrograms per gram). [8] [9] Of the metal-containing products, 75% claimed good manufacturing practices. [10]
  • Public health data. The New York City health department reviewed 584 remedy samples collected from 2010 to 2019 [11] and concluded that rasa shastra Ayurvedic medications can contain very high levels of lead, mercury and arsenic. [12] Adult rasa shastra users had higher average blood lead than users of other remedies. [13]
  • Not only rasa shastra. Mercury was also measured in nine Ayurvedic supplements that are not rasa shastra, from 0.002 to 56 micrograms per gram. [14]

Regulator statements

  • United States (FDA page, current as of 12/02/2025, read 2026-10-22). FDA says there are no FDA-approved Ayurvedic products and that Ayurvedic products marketed to prevent, treat or cure disease are illegally marketed in the US. [15] [16] It reported that an FDA laboratory found high levels of lead and mercury, and the presence of arsenic, in Rheumacare Ayurvedic Proprietary Medicine bought online, after an adverse event report of extremely elevated blood lead. [17] FDA says it adds companies to import alerts to help stop such products entering the US. [18]
  • Canada (Health Canada advisory, 28 January 2019, read 2026-10-22). After the BC Centre for Disease Control informed Health Canada of a case of heavy metal toxicity, [19] laboratory testing identified lead and mercury in products from A1 Herbal Ayurvedic Clinic Ltd. in Surrey, BC. [20] Health Canada says children, pregnant women and breastfeeding women are most susceptible to the toxic effects. [21]
  • India (CCRAS guideline document, read 2026-10-22). Schedule E1 of the Drugs and Cosmetics Act lists poisonous substances in the Ayurvedic system. The mineral-origin entries include parada, hartala, manahashila and hingula, and rasa karpura. [22] India's own guideline test list for bhasma includes particle size, ash values and traditional checks such as lusterless, floating on water and tasteless, and in the list we read does not carry the separate lead, cadmium, mercury and arsenic line that the lists for powders, tablets and oils do. [23]

What studies found, by type of evidence

QuestionWhat the source foundStrength
Do purified preparations cause harm in animals?Rats given three herbal or herbo-metallic products for 28 days had no significant change in cognitive function or oxidative stress markers, [24] but brain metal levels were higher than controls. [25] A rat study of tamra bhasma found no toxicity signs at the therapeutic dose [26] and mild liver, kidney, heart and thymus toxicity at ten times the therapeutic-equivalent dose. [27]Preclinical, small
What do reviews conclude about naga bhasma (lead-based)?The review found no compelling evidence of toxic manifestations, [28] but elemental analysis of preparations showed extremely high lead content. [29]Narrative review
Human harmA case report describes severe liver injury needing listing for transplant after bhasma taken for dyspepsia. [30] [31] A 5-month-old given rasa karpura for constipation developed mercury toxicity and was admitted to intensive care. [32] [33]Case reports, evidence of harm
Do bhasma work in people?A case report authors note bhasma are widely recommended in the absence of good quality clinical trial evidence on safety and efficacy. [34]Proper evidence not found (searched PubMed and Europe PMC; only preclinical and standardization studies surfaced)

A 2014 review says standardization of bhasma is necessary and that these formulations lack complete standardization by physicochemical parameters. [35] Review-literature claims that bhasma are "nanomedicines" or remove heavy metals from the body were not tested in any clinical trial we read.

Practical guidance

  • Be most cautious with products that name bhasma, rasa, sindura, parad or "mineral" or "metal" preparations, and with imported products or products bought online. A label that claims good manufacturing practice does not prove a product is clean. [10]
  • Ask the seller for a batch-specific independent laboratory report for lead, mercury and arsenic. If none exists, that is information.
  • Do not give these products to babies or children, or use them in pregnancy or breastfeeding. FDA notes that metals in a mother's body may pass into breast milk. [36]
  • Tell your doctor about any Ayurvedic product. Clinicians can order tests if heavy metal exposure is suspected. Do not start any "detox" or chelation product on your own.

Who should seek care first

Anyone with unexplained fatigue, abdominal pain, high blood pressure, tingling or weakness in the hands or feet, confusion or dizziness who uses Ayurvedic products should tell a clinician. These are symptoms FDA lists for chronic heavy metal exposure. [37]

Related pages

Frequently asked questions

Does purification make bhasma safe?

The tradition says purified metals are used. [6] Testing found toxic levels in some rasa shastra products anyway, and case reports document serious harm. [8] [30]

Are all Ayurvedic products rasa shastra?

No. Rasa shastra is one section of Ayurvedic pharmacy. In the 2008 online study, 17.1% of the non-rasa shastra products still had detectable metals, versus 40.6% of rasa shastra products. [8]

Can I tell from the label if a product has metals?

Not reliably. FDA says these products typically are not labeled to contain heavy metals such as lead, mercury or arsenic. [7]

Are Ayurvedic mineral products approved in the US?

FDA says there are no FDA-approved Ayurvedic products. [15]

What should I do if I think I took a contaminated product?

Contact a poison center (1-800-222-1222 in the US) or your health care provider, bring the product, and do not self-treat. In the US you can report a suspected product to FDA's MedWatch program. [1]

References
  1. FDA, FDA warns about heavy metal poisoning associated with certain unapproved ayurvedic drug products (content current as of 12/02/2025), consumer advice. Read 2026-10-22.
  2. Sikder, Ayurvedic Medicine: A Traditional Medical System and Its Heavy Metal Poisoning (2024). Read 2026-10-22.
  3. Sikder (2024), Ayurvedic Formulary of India statement. Read 2026-10-22.
  4. Bhasma: the ancient Indian nanomedicine. J Adv Pharm Technol Res 2014. Read 2026-10-22.
  5. Bhasma: the ancient Indian nanomedicine (2014), history. Read 2026-10-22.
  6. Sikder, Ayurvedic Medicine: A Traditional Medical System and Its Heavy Metal Poisoning (2024), full text, purification. Read 2026-10-22.
  7. FDA, FDA warns about heavy metal poisoning associated with certain unapproved ayurvedic drug products (content current as of 12/02/2025), label statement. Read 2026-10-22.
  8. Saper et al., JAMA 2008, rasa shastra comparison. Read 2026-10-22.
  9. Saper et al., JAMA 2008, mercury concentration. Read 2026-10-22.
  10. Saper et al., JAMA 2008, good manufacturing claims. Read 2026-10-22.
  11. Health Remedies as a Source of Lead, Mercury, and Arsenic Exposure, New York City (2022), samples. Read 2026-10-22.
  12. Health Remedies as a Source of Lead, Mercury, and Arsenic Exposure, New York City, 2010-2019. Am J Public Health 2022. Read 2026-10-22.
  13. Health Remedies as a Source of Lead, Mercury, and Arsenic Exposure, New York City, 2010-2019 (2022), blood lead. Read 2026-10-22.
  14. Abdalla and Smith, Determination of mercury in ayurvedic dietary supplements that are not rasa shastra. Int J Anal Chem 2013. Read 2026-10-22.
  15. FDA, FDA warns about heavy metal poisoning associated with certain unapproved ayurvedic drug products (content current as of 12/02/2025), approval statement. Read 2026-10-22.
  16. FDA, FDA warns about heavy metal poisoning associated with certain unapproved ayurvedic drug products (content current as of 12/02/2025), legal status. Read 2026-10-22.
  17. FDA, FDA warns about heavy metal poisoning associated with certain unapproved ayurvedic drug products (content current as of 12/02/2025), Rheumacare testing. Read 2026-10-22.
  18. FDA, FDA warns about heavy metal poisoning associated with certain unapproved ayurvedic drug products (content current as of 12/02/2025), import alert. Read 2026-10-22.
  19. Health Canada, A1 Herbal Ayurvedic Clinic Ltd. advisory (January 28, 2019), trigger. Read 2026-10-22.
  20. Health Canada, Health Canada warns that products sold by A1 Herbal Ayurvedic Clinic Ltd. may pose serious health risks (advisory dated January 28, 2019). Read 2026-10-22.
  21. Health Canada, A1 Herbal Ayurvedic Clinic Ltd. advisory (January 28, 2019), susceptibility. Read 2026-10-22.
  22. CCRAS, Ministry of AYUSH, India, General Guidelines for Drug Development of Ayurvedic Formulations (first edition 2018), Schedule E1 list (Ayurvedic mineral entries: Gauripashna, Hartala, Manahashila, Parada, Rasa Karpura, Tuttha, Hingula). Read 2026-10-22.
  23. CCRAS, Ministry of AYUSH, India, General Guidelines for Drug Development of Ayurvedic Formulations (first edition 2018), bhasma test list. Read 2026-10-22.
  24. Evidence for safety of Ayurvedic herbal, herbo-metallic and Bhasma preparations... in rats (2012), results. Read 2026-10-22.
  25. Evidence for safety of Ayurvedic herbal, herbo-metallic and Bhasma preparations on neurobehavioral activity and oxidative stress in rats. Ayu 2012. Read 2026-10-22.
  26. Acute and subchronic toxicity study of Tamra Bhasma (2016), therapeutic dose. Read 2026-10-22.
  27. Acute and subchronic toxicity study of Tamra Bhasma (incinerated copper) prepared with and without Amritikarana. J Ayurveda Integr Med 2016. Read 2026-10-22.
  28. Safety and toxicity issues associated with lead-based traditional herbo-metallic preparations (2014), conclusion. Read 2026-10-22.
  29. Safety and toxicity issues associated with lead-based traditional herbo-metallic preparations. J Ethnopharmacol 2014. Read 2026-10-22.
  30. Ayurveda metallic-mineral 'Bhasma'-associated severe liver injury. BMJ Case Rep 2018. Read 2026-10-22.
  31. Ayurveda metallic-mineral 'Bhasma'-associated severe liver injury (2018), case. Read 2026-10-22.
  32. The Ayurvedic Remedy Rasa Karpura and a Case of Inorganic Mercury Toxicity (2025). Read 2026-10-22.
  33. The Ayurvedic Remedy Rasa Karpura and a Case of Inorganic Mercury Toxicity (2025), outcome. Read 2026-10-22.
  34. Ayurveda metallic-mineral 'Bhasma'-associated severe liver injury (2018), evidence statement. Read 2026-10-22.
  35. Bhasma: the ancient Indian nanomedicine (2014), standardization. Read 2026-10-22.
  36. FDA, FDA warns about heavy metal poisoning associated with certain unapproved ayurvedic drug products (content current as of 12/02/2025), breastfeeding statement. Read 2026-10-22.
  37. FDA, FDA warns about heavy metal poisoning associated with certain unapproved ayurvedic drug products (content current as of 12/02/2025), symptom list. Read 2026-10-22.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.