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Meridians and Collaterals as a Traditional Framework

What meridians and collaterals are in traditional Chinese medicine, how the idea developed, and what electrical, anatomical and imaging studies have and have not found.

Content last updated . This page has not been medically reviewed.

A traditional map of the body

In traditional Chinese medicine (TCM), meridians (jing) and collaterals (luo) are the channels along which qi and blood are said to travel, linking the body surface with the internal organs. A review of the Huangdi Neijing (Yellow Emperor's Inner Classic) says the text describes the pathways of main, collateral and "curious" vessels and the circulation of blood and qi. [1] A researcher in the acupuncture field describes meridians as traditionally believed to be channels connecting the surface of the body to internal organs. [2]

This is a traditional framework. Acupuncture points are described as lying along these channels, which is why the meridian map is used in acupuncture. For the practice itself and its evidence see What Is Acupuncture? and Acupuncture Methods.

How the idea developed

The meridian system was not written down all at once. A review of a book on the history of the theory says meridians evolved over time: in the Qin and Han dynasties six meridians were developed on the basis of six types of qi, and in terms of "six types of qi and five elements" five zang organs, six fu organs and eleven meridians were structured. It then describes twelve meridians being composed by correspondence with celestial cycles. [3] A history of body diagrams adds that illustrations focused on meridian theory used zang-fu organ metaphors to explain acupuncture taboos. [4] For the organs see Zang-Fu; for qi see What Is Qi?; for the framework as a whole see Qi, Yin and Yang, Five Phases and Meridians.

What studies have looked for

Researchers have tried to find a physical basis for meridians for decades. The main lines of work, and what they found, are below. The strength labels use this site's evidence scale.
QuestionWhat the source foundStrength
Are points and meridians electrically different from nearby skin?A systematic review of 16 articles (18 studies) found 5 of 9 point studies and 7 of 9 meridian studies reporting lower electrical resistance or impedance, but the studies were generally poor in quality, small and confounded; the review concluded the evidence does not conclusively support the claim [5]Insufficient evidence
A careful follow-up measurementIn 23 people, impedance was lower along the Pericardium meridian than a control line but not along the Spleen meridian; ultrasound suggested contact of the needle with connective tissue may explain the difference [6]Insufficient evidence
Do points line up with connective tissue?In sections through the human arm, about 80% of acupuncture point sites corresponded to intermuscular or intramuscular connective tissue planes [2]Promising but limited: a hypothesis-generating anatomical study that does not show meridians exist
Is there a structure at the point?A Chinese-language review of studies of skin, nerves, vessels and cells said understanding still lags behind what is needed [7]Insufficient evidence
Can a specific cell type explain meridians?A study in vertebrate tissue proposed telocytes, long connective-tissue cells, as an analogue of meridian maps [8]Preclinical

Modern interpretations and proposals

Several recent papers propose that meridians might map onto known structures. These are proposals, not established facts:
  • An acupuncture article in the Journal of Alternative and Complementary Medicine argued that failing to use clear terminology and to rigorously investigate acupuncture points has hindered acupuncture's legitimacy as an evidence-based therapy, and called for rigorous tests of their specificity and possible biological basis. [9]
  • A 2025 paper on "structure-based" acupuncture suggests some meridians correspond to fascia chains, blood vessels or nerves, and says some meridians such as Bladder and Gallbladder are myofascial meridians while the Lung and Pericardium may be vessels or nerves. [10] This is one clinician's model.
  • A 2026 hypothesis paper proposes that the traditional sanjiao-mocou concept is analogous to the fascial-interstitial system, which it says would provide a testable model of meridians. [11]
  • A 2026 proposal would treat meridians as functional networks in a body-based coordinate system, shifting research from debates about what they are to testable questions about how stimulation effects are spatially distributed. [12]

An author of one paper on the body as an electronic circuit states plainly that there is no clear evidence that acupuncture points and meridians are separate organs or specific tissues. [13] In summary: the meridian system is a long-standing map used in practice, and no one has shown a single anatomical structure that corresponds to it.

Does it matter for acupuncture?

Whether meridians exist as structures is a different question from whether acupuncture or acupressure helps a specific problem. Trials decide the second question, and the answer differs by condition: see Acupuncture for Back and Neck Pain, Acupressure and TCM Evidence by Use. An overview of 104 Cochrane reviews on TCM found only 5 with overall positive conclusions, 42 with insufficient evidence and 54 without firm conclusions. [14] For general guidance on reading trials see Understanding Evidence.

Frequently asked questions

Do meridians physically exist?

A systematic review found the evidence did not conclusively support the claim that points or meridians are electrically distinguishable. [5] One anatomical study found about 80% of point sites matched connective tissue planes, which suggests a possible link but does not prove meridians. [2]

Are meridians the same as nerves or blood vessels?

No single structure has been shown to match them. One 2025 paper suggests some meridians may follow fascia chains, vessels or nerves, but that is one model. [10]

Do I need to believe in meridians for acupuncture to work?

Trials test whether acupuncture changes outcomes, whatever the theory. See What Is Acupuncture?.

What are collaterals?

In the tradition they are named alongside the main meridians. The Huangdi Neijing review mentions main, collateral and "curious" vessels. [1] We did not find a source read this round that describes the collaterals in more detail, so this page does not.

Can I find and press my own meridians?

Gentle acupressure is covered at Acupressure. Ask a qualified practitioner or clinician first if you are pregnant or have a health condition.

More details: evidence, limits and cautions

The details behind this page: cautions, limits of the evidence and where sources disagree. Open any note to read it.

Safety note
Meridian charts are not a self-treatment guide. Do not needle yourself. Acupuncture should be done by a trained practitioner. Do not delay care for new, severe or worsening symptoms because a traditional explanation sounds reassuring. NCCIH advises not using TCM to replace or delay seeking conventional care. [15] Licensing varies by place: see Acupuncture Practitioner Licensing and Training.
References
  1. Cavalieri. Huangdi Neijing: a classic book of traditional Chinese medicine. Recenti Progressi in Medicina 1997. PubMed 9446158. Read 2026-10-22.
  2. Langevin HM, Yandow JA. Relationship of acupuncture points and meridians to connective tissue planes. Anatomical Record 2002. PubMed 12467083. Read 2026-10-22.
  3. Zhu. Evolution of meridian theory (book review). Zhongguo Zhen Jiu 2025. PubMed 40229165. Read 2026-10-22.
  4. Cui. Exploring the drawings and the evolution of human body diagrams about Zang-Fu organs and meridians. Zhonghua Yi Shi Za Zhi 2026. PubMed 42893925. Read 2026-10-22.
  5. Ahn AC et al. Electrical properties of acupuncture points and meridians: a systematic review. Bioelectromagnetics 2008. PubMed 18240287. Read 2026-10-22.
  6. Ahn AC et al. Electrical impedance along connective tissue planes associated with acupuncture meridians. BMC Complementary and Alternative Medicine 2005. PubMed 15882468. Read 2026-10-22.
  7. She. Considerations about studies on the structure of acupuncture points. Zhen Ci Yan Jiu 2018. PubMed 29888561. Read 2026-10-22.
  8. Yonghong et al. Telocytes in different organs of vertebrates: potential essence cells of the meridian in Chinese traditional medicine. Microscopy and Microanalysis 2020. PubMed 32390582. Read 2026-10-22.
  9. Langevin HM et al. What is the point? The problem with acupuncture research that no one wants to talk about. Journal of Alternative and Complementary Medicine 2018. PubMed 29493256. Read 2026-10-22.
  10. Tang. Structure-based medical acupuncture: new perspective on an ancient technique. Medical Acupuncture 2025. PubMed 40547386. Read 2026-10-22.
  11. Xia. The fascial-interstitial system and the sanjiao-mocou system: an analogy-based hypothesis for the anatomical basis of meridian pathways. Frontiers in Physiology 2026. PubMed 41971664. Read 2026-10-22.
  12. Ryu Y, Chae Y. Meridian systems as spatiotemporal networks: an internal body geographic information system. Journal of Integrative Medicine 2026. PubMed 42692968. Read 2026-10-22.
  13. Strakhova. The body as an electronic scheme. Journal of Acupuncture and Meridian Studies 2024. PubMed 38898644. Read 2026-10-22.
  14. Dai et al. Cochrane systematic reviews on traditional Chinese medicine: what matters, the quantity or quality of evidence? Phytomedicine 2022. PubMed 35104758. Read 2026-10-22.
  15. National Center for Complementary and Integrative Health (NCCIH, US). Traditional Chinese Medicine: What You Need To Know. Read 2026-10-22.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.